Nguyen Lab

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Publications

  1. Nguyen, A.L. Smith, E., Losada, A., Cheeseman, I.M. (2025) Co-Essentiality Analysis Identifies PRR12 as a Cohesin Interacting Protein and Contributor to Genomic Integrity. Developmental Cell. 
  2. Nguyen, A.L. Fadel, M.D., Cheeseman, I.M. (2021). “Differential Requirements for the    CENP-O Complex Reveal Parallel PLK1 Kinetochore Recruitment Pathways”. Molecular Biology of the Cell. 32(8):712-721. PubMed PMID: 33596090.
  3. Blengini, C.S., Nguyen, A.L., Aboelenain, M., Schindler K. (2022). “Age-dependent integrity of the meiotic spindle assembly checkpoint in females requires Aurora kinase B”. Aging Cell. 20(11). e13489. PubMed PMID: 34704342.
  4. Nguyen, A.L., Drutovic, D., Gentilello, A., Malumbres, M., Solc, P., Schindler K.  (2018). “Genetic interactions between the Aurora kinases reveal new requirements for AURKB and AURKC during oocyte meiosis”. CurrentBiology. 28 (21): 3458-3468 PubMed PMID: 30415701.
  5. Marin, D.*, Nguyen, A.L*., Schindler, K. (2018). “Using mouse oocytes to access human gene function during Meiosis I”. *Equal contribution. J. Vis. Exp. (134). e57442. PubMed PMID: 29708548.
  6. Pascottini, O.B., Goszczynski, D.E., Nguyen, A.L. (2017). “Creating Chimeras: Embryonic stem cells incorporated”. Molecular Reproduction & Development. 85: 85-85.
  7. Nguyen, A.L., Marin, D., Zhou, A., Cao, Z., Fedick, A., Wang, Y., Taylor, D., Scott, R.T., Xing, J. Treff, N. Schindler, K. (2017). “Identification and characterization of Aurora Kinase B and C Variants associated withmaternal aneuploidy”. Molecular Human Reproduction. 23(6): 406-416. PubMed PMID: 28369513.
  8. Nguyen, A.L. Schindler, K. (2017). “Specialize and divide (twice). Functions of the three Aurora kinase homologsin mammalian oocyte meiotic maturation”. Trends  in Genetics. 33(5): 349-363. PubMed PMID:28359584.
  9. Schang, G., Fernandez-Fuertes, B., Lean, S.C., Nguyen, A.L., Pascottini, O.B. (2017). “ Infinity sperm storage: The gift that keeps on giving”. Molecular Reproduction &. Development. 84(8). 667-667.
  10. Radford, S., Nguyen, A.L., Schindler, K., McKim, K. (2016). “The chromosome basis of       acentrosomal spindle assembly and function”. Chromosoma. 126(3): 351-364. PubMed PMID: 27837282.
  11. Balboula, A.Z., Nguyen, A.L., Gentilello, A.S., Quartuccio, S.M., Drutovic, D., Solc, P., Schindler, K. (2016). “Haspin kinase regulates microtubule-organizing center clustering and stability through Aurora kinase C in mouse oocytes”. Journal of Cell  Science. 129(19): 3648-3660. PubMed PMID: 27562071.
  12. Nguyen, A.L., Gentilello A., Balboula A., Shrivastava V., Ohring J., Schindler K. (2014). “Phosphorylation of Threonine 3 on Histone 3 by Haspin Kinase is Required  for Meiosis I in Mouse Oocytes”. Journal of Cell Science.127(23): 5066-5078.  PubMed PMID: 25315835.
  13. Chu H., Liao Y., Novak J., Hu J., Merkin J.J., Shymkiv Y., Braeckman B., Dorovkov M., Nguyen A., Clifford P.,Nagele R., Harrison D., Ellis R., Ryazanov A.G. (2014). “Germline quality control: eEF2K stands guard to eliminate defective oocytes”. Developmental Cell. 28(5): 561-572. PubMed PMID: 24582807.

Coming soon!

  1. Dudka, D., Nguyen, A.L., Boese, K., Marescal, O. Akins, B., Black, B.E., Cheeseman, I.M., Lampson, M.A. Bi-directional modulation of centromere binding via evolutionary innovation in the CENPT histone fold domain.
  2. Pare, H., Nguyen, A.L., Cheeseman, I.M, Plachetzki, D. Molecular divergence of the kinetochore reveals insights into the structural constraints and drivers in macromolecular structure evolution. 

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