How do cells regulate their genomes?
Our Big Question:
We are fascinated with understanding how cells organize, protect, and segregate their genomes and how these processes can be rewired across different cellular contexts. To answer these questions we use mammalian cell lines and mouse models and a combination of high-resolution imaging, functional genetics, and large-scale screens. Our approach is to harness the context-specific gene requirements that are intrinsic to organismal function as a key to unraveling the mechanisms that govern chromosome biology and define how alterations in core cellular processes influence disease, development, and evolution.
News!
- Congratulations to Molly for being awarded the Howell Travel Award!
- Congratulations to Molly for her acceptance to the CSHL Chromatin, Epigenetic, and Gene Expression course!
Aly Nguyen with postdoctoral researcher, Molly Zych in her lab. - Ally has been named a Boettcher Investigator!
We are thrilled to represent the University of Colorado, Anschutz Medical school as a recipient of the Boettcher Webb-Waring Biomedical Research Award. This grant will support our work exploring the role of PRR12 in the regulation of the Cohesin complex in the repair of damaged DNA.
- First official lab photo!
- We are officially up and running!!!
First agarose gels! 
Our first PCR! PRR12 mutant constructs 
Tissue Culture is setup!
Join Us
Postdoctoral Fellows
We welcome applications from potential postdoctoral fellows. Please email Ally with a short research description, CV, and contact information for 3 references.
Graduate Students
CU graduate students can join the lab through a rotation. Please contact Ally to learn more about rotation opportunities.
Contact Us
University of Colorado School of Medicine
Department of Cell and Developmental Biology
Research 1 South, Room 12113
12801 E. 17th Ave
Aurora, CO 80045